Description

4-Phenyl-1-Propyl-3,5,8-Trioxabicyclo[2.2.2]Octane is a specialized bicyclic acetal compound, valued for its unique structural framework that serves as a versatile building block and protective group in advanced organic synthesis. Its rigid, cage-like structure is particularly significant for introducing steric and electronic control in the development of complex molecules, including pharmaceuticals and functional materials. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and optimize synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthon or protecting group in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring controlled stereochemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its acetal functionality can modulate bioavailability and stability.
• Ligand and Catalyst Development: Acts as a precursor or backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Incorporated into monomers or additives to impart specific thermal or chemical resistance properties to advanced polymers and resins.
• Flavor and Fragrance Chemistry: Employed in the synthesis of complex aroma chemicals that require stable, masked carbonyl equivalents.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, exploring new reactions and mechanisms involving acetals and ethers.

Basic Information

Product Name	4-Phenyl-1-Propyl-3,5,8-Trioxabicyclo[2.2.2]Octane
CAS No.	70637-03-5
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	1-Propyl-4-phenyl-3,5,8-trioxabicyclo[2.2.2]octane; 3,5,8-Trioxabicyclo[2.2.2]octane, 4-phenyl-1-propyl-; Phenylpropyltrioxabicyclooctane; Bicyclic acetal 70637-03-5; 4-Phenyl-1-propyl-1,3,5-trioxa-8-azabicyclo[3.2.1]octane (related structural isomer); Acetal protecting group intermediate
EINECS	Contact for details

Quality Control

Our 4-Phenyl-1-Propyl-3,5,8-Trioxabicyclo[2.2.2]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and moisture to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.