Description

4-tert-Butyl-1-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane is a high-purity bicyclic orthoester compound, valued for its role as a versatile chemical building block and protecting group in advanced organic synthesis. Its unique cage-like structure provides exceptional stability under basic conditions while offering selective reactivity, making it a critical reagent for demanding pharmaceutical and fine chemical manufacturing processes. This compound is essential for researchers and production chemists in the pharmaceutical, agrochemical, and specialty materials industries who require reliable, high-quality intermediates for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Serves as a key protecting group for diols and polyols in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly in nucleoside and carbohydrate chemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where selective protection of hydroxyl groups is required.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored thermal and chemical properties.
• Fine Chemical Production: Employed as a precursor or reagent in the synthesis of complex fragrance compounds, dyes, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable tool in research laboratories for methodology development and exploring new synthetic routes due to its well-defined reactivity profile.

Basic Information

Product Name	4-tert-Butyl-1-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane
CAS No.	70636-88-3
Molecular Formula	C10H18O3
Molecular Weight	186.25 g/mol
Synonyms	1-Methyl-4-tert-butyl-2,6,7-trioxabicyclo[2.2.2]octane; 4-tert-Butyl-1-methyl-2,6,7-trioxabicyclo[2.2.2]octane; tert-Butyl methyl bicyclic orthoester; Bicyclic orthoester; TBO; 2,6,7-Trioxabicyclo[2.2.2]octane, 4-(1,1-dimethylethyl)-1-methyl-; 4-(tert-Butyl)-1-methyl-2,6,7-trioxabicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-1-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, GC for residual solvents, and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.