Description

4-Amino-2,2,6,6-Tetramethylpiperidine-D17-1-Oxyl is a deuterated, stable nitroxide radical derivative of the TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) family. This compound matters as a crucial spin label and probe in advanced spectroscopic techniques, particularly Electron Paramagnetic Resonance (EPR) spectroscopy, where its deuterated structure provides enhanced spectral resolution and sensitivity. Researchers and developers in pharmaceuticals, polymer science, and materials chemistry need it for studying molecular dynamics, protein structure, and radical polymerization processes with high precision.

Application

• EPR/ESR Spectroscopy: As a deuterated spin label for probing biomolecular structures, membrane fluidity, and protein dynamics with reduced spectral line broadening.
• Polymer Chemistry: Acting as a mediator in controlled/living radical polymerization (e.g., ATRP, NMP) and as a stabilizer against thermal degradation.
• Biophysical Research: Site-directed spin labeling (SDSL) of proteins and nucleic acids to investigate conformational changes and interactions.
• Antioxidant Studies: Serving as a model compound to study radical scavenging activity and oxidative stress mechanisms.
• Materials Science: Use as a dopant or probe in the development of organic semiconductors, magnetic materials, and functional coatings.
• Analytical Chemistry: Employed as a standard or reference material in chromatographic and spectroscopic method development.
• Pharmaceutical Research: Utilization in drug delivery system studies to track release kinetics and carrier integrity.
• Catalysis: Application as a co-catalyst or redox mediator in selective oxidation reactions.

Basic Information

Item	Detail
Product Name	4-Amino-2,2,6,6-Tetramethylpiperidine-D17-1-Oxyl
CAS No.	70588-04-4
Molecular Formula	C9D17N2O
Molecular Weight	191.34 g/mol (approx.)
Synonyms	4-Amino-TEMPO-d17; Perdeuterated 4-Amino-TEMPO; 4-Amino-2,2,6,6-tetramethylpiperidin-1-oxyl-d17; 4-AT-d17; 4-Amino-2,2,6,6-tetramethyl-1-oxylpiperidine-d17; 4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-2,2,6,6,3,3,5,5,4,4,α,α,β,β,γ,γ,δ,δ-d17; 4-Aminopiperidinooxy-d17
EINECS	Contact for details

Quality Control

Our 4-Amino-2,2,6,6-Tetramethylpiperidine-D17-1-Oxyl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity, isotopic enrichment, and radical stability. Certificates of Analysis (COA) detailing specifications for assay, deuterium content, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Content (NMR/MS)	≥ 98 atom % D
EPR Assay	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.