Description

5-Cyano-4-Methyl-3-Phenyl-2-Thiophenecarboxamide is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a thiophene ring with cyano, phenyl, and carboxamide functionalities, making it a versatile precursor for complex molecular frameworks. This compound is primarily needed by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Acts as a monomer or functional additive in the synthesis of advanced polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Synthesis: Employed in the creation of specialized dyes and pigments due to the electron-rich thiophene and cyano groups that influence color and stability.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems used in cross-coupling and other organic transformations.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry, including cyclization and functional group transformation reactions.

Basic Information

Product Name	5-Cyano-4-Methyl-3-Phenyl-2-Thiophenecarboxamide
CAS No.	70541-99-0
Molecular Formula	C13H10N2OS
Molecular Weight	242.30 g/mol
Synonyms	5-Cyano-4-methyl-3-phenylthiophene-2-carboxamide; 2-Thiophenecarboxamide, 5-cyano-4-methyl-3-phenyl-; 3-Phenyl-5-cyano-4-methyl-2-thiophenecarboxamide; 4-Methyl-3-phenyl-5-cyano-2-thiophenecarboxamide; 5-Cyano-4-methyl-3-phenyl-2-carbamoylthiophene; Thiophene-2-carboxamide, 5-cyano-4-methyl-3-phenyl-; 70541-99-0; 5-Cyano-4-methyl-3-phenylthiophene-2-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 5-Cyano-4-Methyl-3-Phenyl-2-Thiophenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.