Description

5-Cyano-3,4-Dimethylthiophene-2-Carboxamide is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used as a building block in the creation of novel pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor for the synthesis of advanced organic electronic materials, such as conductive polymers or organic semiconductors.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for metal complexes and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes and tools to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up manufacturing under cGMP or ISO standards.

Basic Information

Product Name	5-Cyano-3,4-Dimethylthiophene-2-Carboxamide
CAS No.	70541-97-8
Molecular Formula	C8H8N2OS
Molecular Weight	180.23 g/mol
Synonyms	2-Cyano-4,5-dimethylthiophene-3-carboxamide; 3-Cyano-4,5-dimethyl-2-thiophenecarboxamide; 4,5-Dimethyl-2-thiophenecarboxamide-3-carbonitrile; 5-Cyano-3,4-dimethyl-2-thiophenecarboxamide; 70541-97-8; Thiophene-2-carboxamide, 5-cyano-3,4-dimethyl-
EINECS	Contact for details

Quality Control

Our 5-Cyano-3,4-Dimethylthiophene-2-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of our global clientele in research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.