Description

5-Nitroisoquinoline-1-Carbonitrile is a high-value, multi-functional heterocyclic building block and key synthetic intermediate. Its core value lies in its unique molecular architecture, which combines a nitrated isoquinoline scaffold with a reactive cyano group, enabling the synthesis of complex pharmacophores and advanced materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for targets involving kinase inhibition or other heterocycle-dependent mechanisms.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its nitro and cyano functionalities for bioactivity.
• Organic Synthesis Building Block: A versatile reagent for constructing complex polycyclic nitrogen-containing compounds through cyclization, coupling, and functional group transformation reactions.
• Material Science Precursor: Investigated for the creation of specialized organic ligands, dyes, or photoactive materials due to its conjugated aromatic system.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Nitroisoquinoline-1-Carbonitrile
CAS No.	70538-52-2
Molecular Formula	C₁₀H₅N₃O₂
Molecular Weight	199.17 g/mol
Synonyms	1-Cyano-5-nitroisoquinoline; 5-Nitro-1-isoquinolinecarbonitrile; 5-Nitroisoquinoline-1-carbonitrile; Isoquinoline-1-carbonitrile, 5-nitro-; 70538-52-2; 5-Nitro-1-cyanoisoquinoline
EINECS	Contact for details

Quality Control

Our 5-Nitroisoquinoline-1-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to reliable quality and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.