Description

D-Glucose(6-13C) is a stable isotope-labeled analog of D-glucose, specifically enriched with carbon-13 at the 6th position. This precise isotopic labeling is critical for advanced research applications requiring high specificity and traceability. It is an essential tool for scientists in pharmaceutical development, metabolic research, and analytical chemistry who require reliable, high-purity materials for tracer studies and quantitative analysis. The compound is supplied to meet the stringent demands of modern research and industrial quality control.

Application

• Metabolic Pathway Tracing: Used as a stable isotope tracer in in vivo and in vitro studies to elucidate glucose metabolism, glycolysis, and the pentose phosphate pathway.
• Pharmaceutical Research: Employed in the development and validation of bioanalytical methods, particularly in pharmacokinetic and pharmacodynamic studies for diabetes and metabolic disorder therapeutics.
• Quantitative NMR (qNMR): Serves as a high-purity internal standard or reference material for the quantitative determination of compounds by NMR spectroscopy.
• Mass Spectrometry Standards: Used as an internal standard in LC-MS and GC-MS analyses to ensure accurate quantification of glucose and related metabolites in complex biological matrices.
• Biochemical Research: Applied in enzymatic studies and the investigation of carbohydrate-active enzymes to understand reaction mechanisms and kinetics.
• Nutritional Science: Utilized in stable isotope studies to track nutrient utilization, energy expenditure, and substrate metabolism in nutritional research.

Basic Information

Item	Detail
Product Name	D-Glucose(6-13C)
CAS No.	70491-70-2
Molecular Formula	C512C1H12O6 (C6H12O6 with 13C at position 6)
Molecular Weight	181.15 g/mol (approx.)
Synonyms	D-(6-13C)Glucose; (6-13C)Glucose; D-Glucose-6-13C; 6-13C-Labeled D-Glucose; D-Glucose (6-13C); D-Glucose-13C6 (positional isomer); D-(+)-Glucose-6-13C; Dextrose-6-13C; α-D-Glucopyranose-6-13C
EINECS	Contact for details

Quality Control

Every batch of D-Glucose(6-13C) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. Key parameters such as isotopic enrichment, chemical purity, and optical rotation are rigorously verified. A Certificate of Analysis (COA) detailing batch-specific results, including assay by HPLC and isotopic purity by NMR or MS, is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Isotopic Enrichment	≥ 99 atom % 13C (at position 6)
Optical Rotation	[α]D20: +52.5° to +53.5° (c=10 in H2O)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.