Description

1-Chloro-3-(Iodomethyl)Benzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its dual functionality, offering reactive sites for both nucleophilic substitution and cross-coupling reactions, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated benzyl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the chloromethyl and iodomethyl groups allow for selective derivatization.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-couplings.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers with tailored electronic or photophysical properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactivity of the iodomethyl group under mild conditions.
• Custom Fine Chemical Production: A versatile scaffold for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for client projects.

Basic Information

Product Name	1-Chloro-3-(Iodomethyl)Benzene
CAS No.	70450-41-8
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	3-(Chloromethyl)iodobenzene; 3-Chlorobenzyl Iodide; m-Chlorobenzyl Iodide; 1-Chloro-3-iodomethylbenzene; (3-Chlorophenyl)methyl Iodide; 3-Chloro-α-iodotoluene; 70450-41-8; α-Iodo-3-chlorotoluene
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-(Iodomethyl)Benzene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability, making this material suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame. Due to its light-sensitive and easily oxidized nature, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.