Description

2-Bromo-1,1,1,3,3,3-Hexafluoro-2-(Methoxyphenyl)Propane is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a bromo-hexafluoroisopropyl moiety with a methoxyphenyl group, which enables precise structural modifications in target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and advanced materials with tailored thermal and chemical resistance properties.
• Organic Synthesis Building Block: Acts as a versatile reagent for introducing the hexafluoroisopropyl alcohol (HFIP) group into aromatic systems, facilitating structure-activity relationship (SAR) studies.
• Catalyst and Ligand Development: Utilized in the design and synthesis of novel fluorinated ligands for catalysis in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-1,1,1,3,3,3-Hexafluoro-2-(Methoxyphenyl)Propane
CAS No.	70430-22-7
Molecular Formula	C10H7BrF6O
Molecular Weight	337.06 g/mol
Synonyms	2-Bromo-1,1,1,3,3,3-hexafluoro-2-(4-methoxyphenyl)propane; 1-(4-Methoxyphenyl)-2-bromo-1,1,1,3,3,3-hexafluoropropan-2-ol; α-Bromo-α-(4-methoxyphenyl)hexafluoroisopropanol; 4-Methoxyphenyl Hexafluoroisopropyl Bromide; HFIP-Br Methoxybenzene Derivative; (4-Methoxyphenyl)(bromo)bis(trifluoromethyl)methanol; CAS 70430-22-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and supporting your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) and at a controlled room temperature (15-25°C) to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.