Description

6-Chloro-4-Hydroxy-2-Methyl-2H-Thieno[2,3-E]-1,2-Thiazine-3-Carboxylic Acid Methyl Ester 1,1-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring potent biological activity. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing next-generation medications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel sulfonamide-based drug candidates with potential anti-inflammatory, anti-bacterial, or diuretic properties.
• Organic Synthesis Building Block: Utilized in research and development for constructing complex heterocyclic frameworks due to its reactive chloro, hydroxy, and ester functional groups.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new therapeutic agents.
• Fine Chemical Production: Employed in the multi-step synthesis of specialized, high-value chemicals for agrochemical or material science applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	6-Chloro-4-Hydroxy-2-Methyl-2H-Thieno[2,3-E]-1,2-Thiazine-3-Carboxylic Acid Methyl Ester 1,1-Dioxide
CAS No.	70415-50-8
Molecular Formula	C9H8ClNO5S2
Molecular Weight	309.75 g/mol
Synonyms	Methyl 6-chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylate 1,1-dioxide; 6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester S,S-dioxide; Thienothiazine derivative; CAS 70415-50-8
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Hydroxy-2-Methyl-2H-Thieno[2,3-E]-1,2-Thiazine-3-Carboxylic Acid Methyl Ester 1,1-Dioxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.