Description

2,5-Dibromothiophene-3-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is valued for its dual functionality, enabling the introduction of both bromine and sulfonyl chloride groups to construct complex heterocyclic and pharmaceutical intermediates. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Functional Material Development: Serves as a monomer or cross-linking agent in the production of conductive polymers, organic semiconductors, and specialty coatings.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reaction pathways and creating complex thiophene-based molecular architectures.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and organocatalysts.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast organic dyes and pigments.

Basic Information

Product Name	2,5-Dibromothiophene-3-Sulfonyl Chloride
CAS No.	70374-40-2
Molecular Formula	C4HBr2ClO2S2
Molecular Weight	354.89 g/mol
Synonyms	3-Thiophenesulfonyl chloride, 2,5-dibromo-; 2,5-Dibromo-3-thiophenesulfonyl chloride; 2,5-Dibromothiophene-3-sulphonyl chloride; 2,5-Dibromothiophene-3-SO2Cl; DBTS-Cl; 70374-40-2; Thiophene, 2,5-dibromo-3-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dibromothiophene-3-Sulfonyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed control of key impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and relevant physical data. We support custom synthesis to meet specific purity requirements (e.g., ≥98% or ≥99%) for advanced research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.