Description

1,3-Dihydro-1-Methyl-3-(2-Oxopropylidene)-2H-Indol-2-One is a specialized heterocyclic organic compound belonging to the oxindole class, serving as a valuable synthetic intermediate. Its unique structure makes it a critical building block for the development of complex molecules in advanced research and manufacturing. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex heterocyclic systems and functionalized molecules.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides due to its bioactive indole core.
• Material Science: Investigated for the synthesis of specialty polymers and advanced organic materials with specific electronic or photophysical properties.

Basic Information

Product Name	1,3-Dihydro-1-Methyl-3-(2-Oxopropylidene)-2H-Indol-2-One
CAS No.	70351-51-8
Molecular Formula	C₁₂H₁₁NO₂
Molecular Weight	201.22 g/mol
Synonyms	1-Methyl-3-(2-oxopropylidene)indolin-2-one; 3-(2-Oxopropylidene)-1-methylindolin-2-one; 1-Methyl-3-(2-oxopropylidene)-2-indolinone; 1-Methyl-3-(2-oxopropylidene)oxindole; (Z)-1-Methyl-3-(2-oxopropylidene)indolin-2-one; 1-Methyl-3-(2-oxoprop-1-en-1-yl)indolin-2-one; 70351-51-8
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-1-Methyl-3-(2-Oxopropylidene)-2H-Indol-2-One is produced under strict quality management protocols. We ensure batch-to-batch consistency and high purity through comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.