Description

Morphine 3-Acetate Hydrochloride is a key pharmaceutical intermediate and reference standard derived from morphine. This compound is critical for research and development in medicinal chemistry, particularly in the study of opioid receptor interactions and analgesic pathways. It is primarily utilized by pharmaceutical manufacturers, analytical laboratories, and academic research institutions engaged in neuropharmacology and controlled substance analysis.

Application

• Pharmaceutical Intermediate: Used in the synthesis and research of novel opioid analgesics and their derivatives.
• Analytical Reference Standard: Serves as a high-purity calibrant in HPLC, GC-MS, and other chromatographic methods for quality control and forensic analysis.
• Biochemical Research: Employed in in vitro studies to investigate opioid receptor binding affinity, selectivity, and signal transduction mechanisms.
• Metabolite Studies: Used as a standard in pharmacokinetic and metabolic pathway research related to morphine and its esters.
• Process Development: Acts as a starting material or intermediate in the development and scaling of API (Active Pharmaceutical Ingredient) manufacturing processes.

Basic Information

Product Name	Morphine 3-Acetate Hydrochloride
CAS No.	70192-59-5
Molecular Formula	C20H23NO5 • HCl
Molecular Weight	393.86 g/mol (Free base: 357.40)
Synonyms	3-Acetylmorphine Hydrochloride; Morphine 3-Monoacetate HCl; 3-O-Acetylmorphine Hydrochloride; 7,8-Didehydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol 3-acetate hydrochloride; Heroin Impurity B Hydrochloride; Noracymorphol Hydrochloride (related); Diacetylmorphine Related Compound B HCl
EINECS	Contact for details

Quality Control

Our Morphine 3-Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, which includes data from chromatographic (HPLC) and spectroscopic (IR, NMR) methods. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.