Description

(S)-2-Chloro-1-Phenyl-Ethanol CAS NO 70111-05-6 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure APIs, particularly for cardiovascular and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric transformations like epoxidation and hydrogenation.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the synthesis of complex aroma chemicals and other high-value specialty chemicals.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and stereoselective synthesis research.
• Material Science: Potential monomer or building block for chiral polymers and advanced functional materials.

Basic Information

Product Name	(S)-2-Chloro-1-Phenyl-Ethanol
CAS No.	70111-05-6
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	(S)-2-Chloro-1-phenylethanol; (S)-1-Phenyl-2-chloroethanol; (S)-α-(Chloromethyl)benzyl alcohol; (S)-2-Chloro-1-phenylethan-1-ol; (S)-Phenylethyl chlorohydrin; (S)-Styrene chlorohydrin; (S)-β-Chloro-α-phenylethanol; (1S)-2-Chloro-1-phenylethanol
EINECS	Contact for details

Quality Control

Our (S)-2-Chloro-1-Phenyl-Ethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to rigorous analytical testing, including chiral HPLC, NMR, and GC, to confirm identity, purity, and enantiomeric excess (e.e.). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.