Description

1H-Indole-2-Carboxylic Acid, 5-Bromo-3-Methyl-, Ethyl Ester is a high-purity, synthetically valuable brominated indole derivative. This compound serves as a critical pharmaceutical intermediate and organic building block for advanced research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Organic Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Biochemical Research: Used in the study of enzyme inhibitors and receptor ligands due to its indole core structure.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 5-Bromo-3-Methyl-, Ethyl Ester
CAS No.	70070-22-3
Molecular Formula	C₁₂H₁₂BrNO₂
Molecular Weight	282.13 g/mol
Synonyms	5-Bromo-3-methyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-bromo-3-methyl-1H-indole-2-carboxylate; 5-Bromo-3-methylindole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 5-bromo-3-methyl-, ethyl ester; 70070-22-3; 5-Bromo-3-methyl-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-bromo-3-methylindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 5-Bromo-3-Methyl-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.