Description

(2R)-1-(1H-Indol-3-Yl)Propan-2-Amine is a chiral amine derivative of indole, a key structural motif in many biologically active compounds. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential serotonin receptor modulators and other neuroactive compounds.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, especially in neuroscience and psychiatry.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of indolealkylamine derivatives.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2R)-1-(1H-Indol-3-Yl)Propan-2-Amine
CAS No.	7795-52-0
Molecular Formula	C11H14N2
Molecular Weight	174.24 g/mol
Synonyms	(R)-1-(1H-Indol-3-yl)propan-2-amine; (R)-1-(3-Indolyl)-2-propylamine; (R)-α-Methyltryptamine; (R)-α-MT; (2R)-1-(1H-Indol-3-yl)propan-2-amine; (R)-1H-Indole-3-ethanamine, α-methyl-; (R)-2-(1H-Indol-3-yl)-1-methylethylamine
EINECS	Contact for details

Quality Control

Our (2R)-1-(1H-Indol-3-Yl)Propan-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.