Description

5-Methyl-(S)-(+)-Mellein is a chiral, substituted isocoumarin derivative, a compound class known for its diverse biological activities. This specific enantiomer is of significant interest in advanced organic synthesis and pharmaceutical research due to its role as a key chiral building block and its potential as a bioactive scaffold. It is primarily utilized by research chemists and development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor in the synthesis of complex drug candidates and bioactive molecules.
• Asymmetric Synthesis: Employed as a building block for constructing enantiomerically pure natural products and complex organic frameworks.
• Biochemical Research: Used as a standard or probe in studies investigating enzyme inhibition, receptor binding, or metabolic pathways.
• Agrochemical Development: Investigated for the development of novel, chiral active ingredients with specific modes of action.
• Flavor & Fragrance Chemistry: Acts as a synthetic intermediate for certain musk-like or woody aroma compounds.
• Academic Research: Utilized in universities and research institutes for methodological development in organic chemistry and total synthesis projects.

Basic Information

Product Name	5-Methyl-(S)-(+)-Mellein
CAS No.	7734-92-1
Molecular Formula	C10H10O3
Molecular Weight	178.18 g/mol
Synonyms	(S)-5-Methylmellein; (S)-(+)-5-Methylmellein; (3S)-3,4-Dihydro-5-methyl-8-hydroxy-3-propyl-1H-2-benzopyran-1-one; 5-Methyl-(S)-mellein; (+)-5-Methylmellein; 8-Hydroxy-5-methyl-3-propylisochroman-1-one; Ochracin
EINECS	Contact for details

Quality Control

Our 5-Methyl-(S)-(+)-Mellein is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, potency, and enantiomeric excess meet rigorous standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, optical rotation, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Optical Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.