Description

4,5α-Epoxy-6α-Methoxy-17-Methylmorphinan-3-Ol is a high-purity synthetic intermediate belonging to the morphinan class of compounds. This compound is of significant value in advanced pharmaceutical research and development, particularly for its role as a key precursor in the synthesis of specialized active pharmaceutical ingredients (APIs). It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of analgesic and central nervous system (CNS) targeted therapies.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potent opioid analgesics and related therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities targeting neurological pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of complex morphinan-derived APIs.

Basic Information

Item	Details
Product Name	4,5α-Epoxy-6α-Methoxy-17-Methylmorphinan-3-Ol
CAS No.	7732-92-5
Molecular Formula	C19H25NO3
Molecular Weight	315.41 g/mol
Synonyms	6α-Methoxy-4,5α-epoxy-17-methylmorphinan-3-ol; 6α-Methoxy-4,5-epoxymorphinan-3-ol; 6α-Methoxy-4,5α-epoxy-17-methylmorphinan-3-ol; 6α-Methoxy-4,5-epoxy-17-methylmorphinan-3-ol; 6α-Methoxy-4,5α-epoxy-17-methylmorphinan-3-ol; 6α-Methoxy-4,5-epoxymorphinan-3-ol, 17-methyl-; 6α-Methoxy-4,5α-epoxy-17-methylmorphinan-3-ol (related to oxymorphone synthesis)
EINECS	Contact for details

Quality Control

Our 4,5α-Epoxy-6α-Methoxy-17-Methylmorphinan-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.