Description

1-Cyclopropyl-2-(Triphenylphosphoranylidene)-Ethanone is a specialized organophosphorus reagent, specifically a stabilized ylide, widely used in synthetic organic chemistry. Its primary value lies in its role as a key building block for the synthesis of complex molecules, particularly in the construction of cyclopropane rings and other strained systems via Wittig and related olefination reactions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for complex synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing cyclopropane-containing bioactive molecules, a common motif in drug discovery.
• Agrochemical Active Ingredient Development: Used in the synthesis of novel herbicides, fungicides, and insecticides with cyclopropyl groups.
• Advanced Material Precursors: Serves as a building block for creating specialized monomers or ligands used in polymers and catalysts.
• Academic and R&D Laboratories: A valuable tool for methodological development and the synthesis of novel organic compounds in research settings.
• Wittig Olefination Reactions: Acts as a stabilized ylide for the efficient conversion of carbonyl compounds to alkenes, specifically introducing the cyclopropylketone moiety.
• Process Chemistry and Scale-Up: Suitable for optimization and pilot-scale synthesis of target molecules requiring this specific structural unit.

Basic Information

Product Name	1-Cyclopropyl-2-(Triphenylphosphoranylidene)-Ethanone
CAS No.	7691-76-1
Molecular Formula	C23H21OP
Molecular Weight	344.39 g/mol
Synonyms	(Cyclopropylcarbonylmethylene)triphenylphosphorane; 2-Oxo-1-cyclopropylethylidenetriphenylphosphorane; 1-Cyclopropyl-2-oxoethylidenetriphenylphosphorane; Cyclopropyl(triphenylphosphoranylidene)methyl Ketone; Triphenyl(1-cyclopropyl-2-oxoethylidene)phosphorane; Wittig Reagent (cyclopropyl ketone variant); (1-Cyclopropyl-2-oxoethylidene)triphenylphosphorane
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-2-(Triphenylphosphoranylidene)-Ethanone is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.