Description

1-(Chloromethyl)-1H-Pyrrole-2,5-Dione is a versatile and highly reactive chemical building block, primarily used as an intermediate in organic synthesis. Its core value lies in its ability to introduce the chloromethyl and maleimide functional groups into target molecules, enabling the creation of complex structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require a reliable, high-purity intermediate for advanced chemical processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring maleimide or functionalized alkyl halide moieties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where its reactive sites allow for the construction of novel bioactive molecules.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating specialty polymers, coatings, and resins with tailored properties.
• Bioconjugation Reagent: Utilized in biochemical research for labeling proteins, peptides, and other biomolecules due to the reactivity of the maleimide group with thiols.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing heterocyclic compounds, complex natural product analogs, and other fine chemicals.

Basic Information

Product Name	1-(Chloromethyl)-1H-Pyrrole-2,5-Dione
CAS No.	7685-96-3
Molecular Formula	C5H4ClNO2
Molecular Weight	145.54 g/mol
Synonyms	N-(Chloromethyl)maleimide; 1-(Chloromethyl)maleimide; 1-(Chloromethyl)-2,5-pyrroledione; N-Chloromethylmaleimide; Maleimide, N-(chloromethyl)-; 1H-Pyrrole-2,5-dione, 1-(chloromethyl)-; Chloromethylmaleimide
EINECS	231-672-8

Quality Control

Our 1-(Chloromethyl)-1H-Pyrrole-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.