Description

Etafedrine CAS NO 7681-79-0 is a synthetic sympathomimetic amine belonging to the phenethylamine class. This compound is of significant interest in pharmaceutical research and development due to its structural similarity to other adrenergic agents. It serves as a valuable intermediate for the synthesis of more complex active pharmaceutical ingredients (APIs). Key industries that utilize this chemical include pharmaceutical manufacturing, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of adrenergic receptor-targeting drugs and decongestants.
• Medicinal Chemistry Research: Used as a reference standard or precursor in the development of new therapeutic compounds.
• Biochemical Studies: Employed in pharmacological research to study sympathomimetic activity and receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of specialty APIs.
• Analytical Standard: Serves as a high-purity standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Etafedrine
CAS No.	7681-79-0
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	Etafedrine; N-Ethylnorephedrine; Ethylnorephedrine; α-[(Ethylamino)methyl]benzenemethanol; 2-Amino-1-phenyl-1-propanol, N-ethyl-; (R*,S*)-(±)-N-Ethylnorephedrine; 7681-79-0; Benzenemethanol, α-[(ethylamino)methyl]-
EINECS	231-668-8

Quality Control

Our Etafedrine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided and can be tailored to meet specific client or regulatory standards, including ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.