Description

(+/-)-n-Allylnormetazocine CAS NO 7619-35-4 is a synthetic benzomorphan derivative and a potent sigma receptor ligand with significant research interest in neuropharmacology. This compound serves as a critical reference standard and a key intermediate in the development of novel central nervous system (CNS) active agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and analytical testing facilities engaged in neuroscience, receptor binding studies, and the synthesis of experimental therapeutics.

Application

• Pharmacological Research: Used as a reference standard in receptor binding assays to study sigma (σ) receptor interactions and function.
• Neuroscience Studies: A vital tool for investigating the role of sigma receptors in neurological processes, pain modulation, and potential neuroprotective effects.
• Drug Discovery & Development: Serves as a key chemical intermediate and a structural template in the synthesis of novel CNS-targeting compounds for preclinical evaluation.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.
• Biochemical Tool Compound: Utilized in vitro and in vivo to elucidate signaling pathways and behavioral effects associated with sigma receptor activity.

Basic Information

Product Name	(+/-)-n-Allylnormetazocine
CAS No.	7619-35-4
Molecular Formula	C₁₉H₂₇NO
Molecular Weight	285.43 g/mol
Synonyms	N-Allylnormetazocine; (±)-N-Allylnormetazocine; SKF-10,047; (±)-SKF-10,047; Allylnormetazocine; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol; 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl]acetamide (Note: This is a common misassignment; verify structure); Benzomorphan derivative
EINECS	Contact for details

Quality Control

Our (+/-)-n-Allylnormetazocine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications. We support cGMP-compliant production for advanced pharmaceutical development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.