Description

(5α-Androstan-17β-Yloxy)Trimethylsilane is a high-purity steroidal organosilicon compound, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling precise chemical transformations of the steroidal core while protecting sensitive functional groups, ensuring high-yield, reproducible reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel therapeutic agents and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Hormone Analog Research: Used in medicinal chemistry for the research and development of modified androgen and anabolic steroid analogs.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex, functionalized steroidal molecules in laboratory and pilot-scale production.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of steroidal compounds.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	(5α-Androstan-17β-Yloxy)Trimethylsilane
CAS No.	7604-82-2
Molecular Formula	C22H40OSi
Molecular Weight	348.64 g/mol
Synonyms	17β-[(Trimethylsilyl)oxy]-5α-androstane; 5α-Androstan-17β-ol trimethylsilyl ether; Androstan-17β-yloxytrimethylsilane; 17β-Trimethylsiloxy-5α-androstane; 5α-Androstan-17β-yloxy-trimethylsilane; Androstane TMS ether; 5α-Androstan-17β-ol, trimethylsilyl ether
EINECS	Contact for details

Quality Control

Our (5α-Androstan-17β-Yloxy)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.