Description

Diethyl 2,2-Diethoxyethylphosphonate is a versatile organophosphorus compound, primarily valued as a key synthetic intermediate in the Horner-Wadsworth-Emmons (HWE) olefination reaction. Its significance lies in its ability to facilitate the efficient and stereoselective construction of carbon-carbon double bonds, particularly for generating α,β-unsaturated esters and other valuable olefins. This makes it an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of various active pharmaceutical ingredients (APIs), especially those containing α,β-unsaturated carbonyl moieties.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific olefin structures.
• Fine Chemical Manufacturing: Serves as a pivotal building block for creating complex fragrance compounds, specialty polymers, and liquid crystals.
• Academic & Industrial Research: A staple reagent in organic synthesis laboratories for method development and the construction of novel molecular architectures via the Horner-Wadsworth-Emmons reaction.
• Material Science Precursor: Employed in the synthesis of specialized phosphonate-based ligands, flame retardants, and corrosion inhibitors.

Basic Information

Product Name	Diethyl 2,2-Diethoxyethylphosphonate
CAS No.	7598-61-0
Molecular Formula	C10H23O5P
Molecular Weight	254.26 g/mol
Synonyms	(Diethoxyphosphoryl)acetaldehyde Diethyl Acetal; Diethyl (2,2-Diethoxyethyl)phosphonate; Diethyl [(Diethoxy)methyl]phosphonate; 2,2-Diethoxyethylphosphonic Acid Diethyl Ester; Diethyl P,P-Diethoxyethylphosphonate; Acetaldehyde, (diethoxyphosphinyl)-, diethyl acetal; Tetraethyl (2-oxo-1,2-ethanediyl)bis[phosphonate] (related form); HWE Reagent Precursor
EINECS	231-511-8

Quality Control

Our Diethyl 2,2-Diethoxyethylphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.425 - 1.435
Density (20°C)	1.05 - 1.10 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.