Description

4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol is a high-purity synthetic organic compound belonging to the morphinan class, a structure of significant interest in advanced pharmaceutical research and development. This compound matters as a critical pharmaceutical intermediate or reference standard for the synthesis and analytical study of more complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical R&D laboratories, and contract manufacturing organizations (CMOs) working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of specialized opioid receptor ligands and other morphinan-derived therapeutics.
• Analytical Reference Standard: Used in quality control laboratories for method development, validation, and as a certified reference material (CRM) for HPLC, GC-MS, or NMR analysis.
• Medicinal Chemistry Research: A vital substrate for structure-activity relationship (SAR) studies aimed at developing new analgesics or central nervous system (CNS) agents with improved efficacy and safety profiles.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for the production of target drug candidates under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Used in university and institutional labs for pharmacological studies, biochemical assays, and educational purposes in advanced organic and medicinal chemistry.

Basic Information

Product Name	4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol
CAS No.	7505-40-0
Molecular Formula	C20H27NO3
Molecular Weight	329.44 g/mol
Synonyms	6α-Ethoxy-4,5α-epoxy-17-methylmorphinan-3-ol; 6α-Ethoxy-4,5-epoxy-17-methylmorphinan-3-ol; 4,5α-Epoxy-6α-ethoxy-17-methylmorphinan-3-ol; 6α-Ethoxy-4,5-epoxy-3-hydroxy-17-methylmorphinan; 6α-Ethoxy-4,5α-epoxy-3-hydroxy-17-methylmorphinan; 6α-Ethoxy-4,5-epoxy-17-methylmorphinan-3-ol (non-specific stereochemistry); 6-Ethoxy-4,5-epoxy-17-methylmorphinan-3-ol
EINECS	Contact for details

Quality Control

Every batch of our 4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.