Description

1-Acetyl-3-[(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)Oxy]-1H-Indole is a sophisticated, high-purity synthetic intermediate characterized by its indole core linked to a fully acetylated glucose moiety. This compound matters for its role as a key building block in the synthesis of complex bioactive molecules, offering precise structural control for advanced research and development. It is primarily needed by pharmaceutical and biotechnology companies engaged in the development of glycosylated therapeutics, enzyme inhibitors, and novel chemical entities for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of glycosylated indole derivatives and other complex active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving glycosyltransferases or carbohydrate-processing enzymes.
• Glycoconjugate Synthesis: Serves as a protected glycosyl donor for the preparation of glycoconjugates, glycopeptides, and other carbohydrate-based probes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore the biological activity of novel indole-glycoside hybrids.
• Standards & Reference Materials: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	1-Acetyl-3-[(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)Oxy]-1H-Indole
CAS No.	7497-97-4
Molecular Formula	C24H27NO11
Molecular Weight	505.47 g/mol
Synonyms	1-Acetyl-3-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-1H-indole; 3-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyloxy)-1-acetylindole; 1-Acetyl-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)indole; 1H-Indole-3-ol, 1-acetyl-, 3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside); β-D-Glucopyranoside, 1-acetyl-1H-indol-3-yl 2,3,4,6-tetraacetate
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3-[(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)Oxy]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; the container should be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.