Description

Methyl-D3-Amine Hydrochloride is a stable isotope-labeled derivative of methylamine, where three hydrogen atoms are replaced by deuterium. This compound is essential as a high-purity internal standard and tracer in quantitative analytical methods, ensuring accuracy and reliability in complex sample matrices. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and environmental analysis sectors for method development and validation.

Application

• Internal Standard for Mass Spectrometry (MS): Critical for accurate quantification in LC-MS and GC-MS analysis of pharmaceuticals and their metabolites.
• Metabolic Pathway Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of methylamine-containing compounds.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants.
• NMR Spectroscopy: Serves as a valuable tool in structural elucidation and mechanistic studies due to the distinct properties of deuterium.
• Environmental Analysis: Employed as a tracer in studies monitoring the environmental fate of amines and related pollutants.
• Chemical Synthesis Intermediate: Used in the synthesis of other deuterium-labeled compounds for research purposes.

Basic Information

Product Name	Methyl-D3-Amine Hydrochloride
CAS No.	7436-22-8
Molecular Formula	CD3NH2•HCl
Molecular Weight	70.55 g/mol
Synonyms	Deuterated Methylamine Hydrochloride; (Methyl-d3)amine hydrochloride; Methylamine-d3 hydrochloride; Methylamine-N-d3 hydrochloride; Trimethylamine-d3 hydrochloride (common misnomer); Aminomethane-d3 hydrochloride; Monomethyl-d3-amine hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl-D3-Amine Hydrochloride is manufactured under strict quality systems to ensure high chemical and isotopic purity suitable for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, isotopic enrichment, and impurity profile. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee batch-to-batch consistency and reliability for your critical research and analysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.