Description

1H-Indole-3-Propanoicacid,-α--Hydroxy-,(-α-S)-(9Ci) is a high-purity, chiral indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of pharmaceuticals and bioactive molecules. It is primarily required by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemicals, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation plant growth regulators or pesticides with specific chiral activity.
• Biochemical Research: Employed in studies related to tryptophan metabolism and the synthesis of labeled compounds or probes.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Natural Product Synthesis: A valuable intermediate for the total or semi-synthesis of complex indole alkaloids and other natural products.

Basic Information

Product Name	1H-Indole-3-Propanoicacid,-α--Hydroxy-,(-α-S)-(9Ci)
CAS No.	7417-65-4
Molecular Formula	C₁₁H₁₁NO₃
Molecular Weight	205.21 g/mol
Synonyms	(αS)-α-Hydroxy-1H-indole-3-propanoic acid; (S)-2-Hydroxy-3-(1H-indol-3-yl)propanoic acid; (S)-3-(1H-Indol-3-yl)-2-hydroxypropanoic acid; L-2-Hydroxy-3-(indol-3-yl)propionic acid; (S)-Indole-3-lactic acid; 3-Indolyl-(S)-lactic acid; (S)-ILA; (S)-3-(3-Indolyl)lactic acid
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Propanoicacid,-α--Hydroxy-,(-α-S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.