Description

Diethyl (Benzyloxycarbonylmethyl)Phosphonate, 98 % is a high-purity organophosphorus compound, specifically a phosphonate ester, widely recognized as a key reagent in organic synthesis. Its primary value lies in its role as a stable, activated phosphonate building block for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient synthesis of α,β-unsaturated esters and other complex molecules. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing carbon-carbon double bonds with precise stereochemical control.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing olefin linkages in active pharmaceutical ingredients (APIs) and drug candidates via the Horner-Wadsworth-Emmons reaction.
• Agrochemical Manufacturing: Used in the synthesis of complex molecules for crop protection agents, including herbicides and fungicides.
• Fine Chemical Production: Serves as a versatile building block for synthesizing specialty chemicals, flavors, and fragrances.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Academic & R&D Laboratories: A standard reagent for methodological development in organic chemistry and for creating complex natural product analogs.
• Peptide Mimetic Synthesis: Useful in the preparation of phosphonate-based transition-state analogs and enzyme inhibitors.

Basic Information

Product Name	Diethyl (Benzyloxycarbonylmethyl)Phosphonate, 98 %
CAS No.	7396-44-3
Molecular Formula	C13H19O5P
Molecular Weight	286.26 g/mol
Synonyms	Diethyl (Benzyloxycarbonylmethyl)Phosphonate; (Benzyloxycarbonylmethyl)phosphonic Acid Diethyl Ester; Diethyl (Cbz-methyl)phosphonate; Diethyl [(Benzyloxy)carbonylmethyl]phosphonate; CbzCH2PO(OEt)2; Diethyl (Benzyloxycarbonylmethyl)Phosphonate; Diethyl (Cbz-methyl)phosphonate; Diethyl (N-Cbz-aminomethyl)phosphonate analog
EINECS	Contact for details

Quality Control

Our Diethyl (Benzyloxycarbonylmethyl)Phosphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure it meets the specified 98% purity grade and is free from critical impurities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The compound may be moisture-sensitive; ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.