Description

3-(5-Fluoro-1H-Indol-3-Yl)Propanoic Acid is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both an indole core and a fluorine atom, enabling precise modifications to create novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Biochemical Research: Employed as a probe or precursor in studying enzyme interactions and metabolic pathways due to its specific indole-fluorine structure.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	3-(5-Fluoro-1H-Indol-3-Yl)Propanoic Acid
CAS No.	7394-78-7
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	5-Fluoro-3-indolepropionic Acid; 3-(5-Fluoroindol-3-yl)propanoic Acid; 5-Fluoroindole-3-propionic Acid; β-(5-Fluoro-1H-indol-3-yl)propanoic Acid; 5-Fluoro-1H-indole-3-propanoic Acid; 7394-78-7; 3-(5-Fluoro-1H-indol-3-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our 3-(5-Fluoro-1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.