Description

α-[(tert-Butylamino)Methyl]-p-Hydroxybenzyl Alcohol is a specialized organic compound with a unique molecular structure combining phenolic and amino alcohol functionalities. This chemical serves as a valuable pharmaceutical intermediate and research building block for the synthesis of more complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific steric and electronic properties into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of β-adrenergic receptor agonists and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers requiring its distinct molecular scaffold.
• Organic Synthesis Research: A versatile reagent for introducing the tert-butylamino-methyl-p-hydroxybenzyl moiety in medicinal chemistry and material science.
• Bioconjugation & Linker Chemistry: Potential use in developing chemical linkers for drug-antibody conjugates (ADCs) or diagnostic probes due to its reactive groups.

Basic Information

Product Name	α-[(tert-Butylamino)Methyl]-p-Hydroxybenzyl Alcohol
CAS No.	7376-67-2
Molecular Formula	C12H19NO2
Molecular Weight	209.29 g/mol
Synonyms	4-Hydroxy-α-[(1,1-dimethylethyl)amino]methyl]benzenemethanol; 1-(4-Hydroxyphenyl)-2-(tert-butylamino)ethanol; p-Hydroxy-α-[(tert-butylamino)methyl]benzyl alcohol; α-[(tert-Butylamino)methyl]-4-hydroxybenzyl alcohol; TBAMPHBA; tert-Butylamino(4-hydroxybenzyl)methanol; (RS)-1-(4-Hydroxyphenyl)-2-(tert-butylamino)ethanol
EINECS	Contact for details

Quality Control

Our α-[(tert-Butylamino)Methyl]-p-Hydroxybenzyl Alcohol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.