Description

1-p-Tolyl-Prop-2-Yn-1-Ol is a versatile organic intermediate characterized by its acetylene and alcohol functional groups attached to a tolyl aromatic ring. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, especially those requiring alkyne or propargylic alcohol motifs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides, herbicides, and plant growth regulators where its molecular framework contributes to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of polymers, resins, and advanced organic materials with tailored properties.
• Fine Chemical Production: Utilized in multi-step synthetic routes for producing high-value, low-volume specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including cycloaddition and coupling reactions.

Basic Information

Product Name	1-p-Tolyl-Prop-2-Yn-1-Ol
CAS No.	7342-07-6
Molecular Formula	C10H10O
Molecular Weight	146.19 g/mol
Synonyms	1-(4-Methylphenyl)-2-propyn-1-ol; 4-Methylbenzeneacetaldehyde, α-ethynyl-; 1-(p-Tolyl)-2-propyn-1-ol; 1-(4-Methylphenyl)prop-2-yn-1-ol; p-Tolyl propargyl alcohol; 4-Methyl-α-(1-propynyl)benzenemethanol; 2-Propyn-1-ol, 1-(4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 1-p-Tolyl-Prop-2-Yn-1-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame. Due to its sensitivity, allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.