Description

4α-Phenylcyclohexan-1α-Ol CAS NO 7335-12-8 is a versatile chiral alcohol intermediate characterized by its phenyl-substituted cyclohexanol structure. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily sought after by research and development teams, process chemists, and manufacturers engaged in creating advanced active pharmaceutical ingredients (APIs), liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory research.
• Liquid Crystal Materials: Serves as a core component in the production of advanced liquid crystal displays (LCDs) due to its rigid, substituted cyclohexane ring system.
• Fine Chemical Synthesis: Used as a building block for creating complex fragrance compounds, agrochemicals, and other high-value specialty chemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Polymer Modification: Acts as a monomer or chain modifier in the synthesis of specialty polymers with tailored thermal and mechanical properties.

Basic Information

Product Name	4α-Phenylcyclohexan-1α-Ol
CAS No.	7335-12-8
Molecular Formula	C12H16O
Molecular Weight	176.26 g/mol
Synonyms	trans-4-Phenylcyclohexanol; 4-Phenylcyclohexanol; (1r,4r)-4-Phenylcyclohexan-1-ol; 4-Phenyl-1-cyclohexanol; p-Phenylcyclohexanol; NSC 403697; 4-PCHA; 4-Phenylcyclohexyl alcohol
EINECS	Contact for details

Quality Control

Our 4α-Phenylcyclohexan-1α-Ol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent testing. We provide Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure the material meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans-isomer)
Melting Point	110 - 115 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.