Description

Phenol-2,4,6-D3 is a deuterated isotopologue of phenol, where three hydrogen atoms are replaced with deuterium at the 2, 4, and 6 positions of the aromatic ring. This compound is a critical stable isotope-labeled standard, essential for ensuring accuracy and reliability in quantitative analytical techniques. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors for applications such as internal standardization, metabolic studies, and method development.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in GC-MS and LC-MS analyses to improve data accuracy by correcting for instrument variability and sample preparation losses.
• Metabolic Pathway Tracing: Employed in pharmaceutical and biochemical research to study the metabolism, distribution, and excretion of phenolic compounds using isotope tracing techniques.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent or a probing agent in nuclear magnetic resonance (NMR) studies due to its distinct spectroscopic signature.
• Environmental Analysis: Acts as a labeled surrogate standard for the detection and quantification of phenol and its derivatives in environmental samples like water and soil.
• Pharmaceutical Impurity Profiling: Utilized in method development and validation to identify and quantify process-related impurities and degradants in drug substances and products.
• Chemical Reaction Mechanism Studies: Applied in kinetic isotope effect (KIE) studies to investigate reaction mechanisms and pathways in organic synthesis.

Basic Information

Product Name	Phenol-2,4,6-D3
CAS No.	7329-50-2
Molecular Formula	C6D3H3O
Molecular Weight	98.12 g/mol
Synonyms	Phenol-d3; [2,4,6-2H3]Phenol; Deuterated Phenol (2,4,6-D3); 2,4,6-Trideuterophenol; Hydroxybenzene-d3; Phenol (2,4,6-d3); Benzenol-d3
EINECS	Contact for details

Quality Control

Every batch of Phenol-2,4,6-D3 is produced and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (D atom %), and identification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical parameters to ensure compliance with your research and analytical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.