Description

Glycerol-D8 CAS NO 7325-17-9 is a deuterated analog of glycerol, where all eight hydrogen atoms are replaced with the stable isotope deuterium. This high-purity isotopically labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors for applications in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the accurate quantification of glycerol and related metabolites in complex biological matrices like plasma, serum, and cell culture media.
• NMR Spectroscopy Solvent & Tracer: Serves as a deuterated solvent or a non-interfering tracer in metabolic studies to elucidate biochemical pathways and reaction mechanisms.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and their metabolites.
• Biochemical & Nutritional Research: Acts as a probe in studies of lipid metabolism, glycolysis, and energy homeostasis in model organisms.
• Quality Control & Method Validation: Critical for developing and validating robust analytical methods in compliance with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP).
• Environmental & Food Science Analysis: Applied in trace-level detection and analysis of glycerol and its derivatives in environmental samples and food products.

Basic Information

Product Name	Glycerol-D8
CAS No.	7325-17-9
Molecular Formula	C3D8O3
Molecular Weight	98.14 g/mol
Synonyms	Glycerol-d8; [2H8]-Glycerol; Deuterated Glycerol; 1,2,3-Propanetriol-d8; Glycerin-d8; Trihydroxypropane-d8; Glycyl alcohol-d8; 1,2,3-Trihydroxypropane-d8
EINECS	Contact for details

Quality Control

Our Glycerol-D8 is manufactured under stringent controls to ensure exceptional isotopic and chemical purity, meeting the exacting requirements of analytical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity by NMR and HPLC, and residual solvent content. We adhere to relevant quality standards to support research under GLP and GMP frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which could affect purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment (Atom % D)	≥ 98% (by 1H-NMR or MS)
Chemical Purity (HPLC / NMR)	≥ 98%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.