Description

(+)-Cyclazocine CAS NO 7313-87-3 is a high-purity, enantiomerically pure benzomorphan derivative of significant pharmacological interest. This compound serves as a critical reference standard and research chemical for investigating opioid receptor systems and neuropharmacology. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and analytical testing facilities focused on neuroscience, pain management, and receptor characterization.

Application

• Pharmacological Research: Acts as a potent κ-opioid receptor (KOR) agonist and mu-opioid receptor (MOR) partial agonist/antagonist, making it a vital tool for studying receptor function, signal transduction, and behavioral effects.
• Neuroscience Studies: Used in preclinical research to model and understand the mechanisms of addiction, analgesia, and psychosis, contributing to the development of novel CNS therapeutics.
• Reference Standard: Serves as a certified analytical standard for method development, validation, and quality control in pharmaceutical analysis using techniques like HPLC and LC-MS.
• Biochemical Assay Development: Employed in competitive binding assays and functional tests to screen and evaluate new chemical entities targeting opioid receptors.
• Metabolic Pathway Investigation: Used to study the biotransformation and pharmacokinetic profiles of benzomorphan analogs.

Basic Information

Product Name	(+)-Cyclazocine
CAS No.	7313-87-3
Molecular Formula	C18H25NO
Molecular Weight	271.40 g/mol
Synonyms	(+)-Cyclazocine; Win 29,424; Cyclazocine, (+)-isomer; 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol; (5R,9R,13S,14S)-3-(3-methylbut-2-en-1-yl)-4,5-epoxy-6,14-ethano-6,7,8,14-tetrahydro-4-hydroxy-17-methylmorphinan
EINECS	Contact for details

Quality Control

Our (+)-Cyclazocine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chromatographic profile.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.