Description

(2R,11R)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2α,6α-Methano-3-Benzazocine-8-Ol is a complex, chiral benzazocine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or reference standard for the study of opioid receptor pharmacology and the development of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs) and neuropharmacological probes.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel opioid receptor ligands and analgesic compounds.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical R&D.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies to explore and optimize pharmacological profiles.
• Biochemical Assay Development: Used as a tool compound in receptor binding assays and functional studies to understand opioid receptor interactions.
• Process Chemistry: Intermediate in the development and scale-up of synthetic routes for complex chiral molecules.
• Academic Research: Utilized in university and institutional labs for fundamental studies in neurochemistry and drug discovery.

Basic Information

Product Name	(2R,11R)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2α,6α-Methano-3-Benzazocine-8-Ol
CAS No.	7313-86-2
Molecular Formula	C19H27NO
Molecular Weight	285.43 g/mol
Synonyms	8-Hydroxy-3-(cyclopropylmethyl)-6,11-dimethyl-2,6-methano-3-benzazocine; (2R,11R)-(-)-8-Hydroxy-3-(cyclopropylmethyl)-6,11-dimethyl-2,6-methano-1,2,3,4,5,6-hexahydro-3-benzazocine; (-)-8-OH-CPZ; (-)-8-Hydroxy-CPZ; CPZ-8-ol; Benzazocine derivative 7313-86-2
EINECS	Contact for details

Quality Control

Our (2R,11R)-3-(Cyclopropylmethyl)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2α,6α-Methano-3-Benzazocine-8-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure high chemical and isomeric purity suitable for research applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.