Description

(Trimethylsilyl)Acetylene-D is a deuterated organosilicon compound, specifically the deuterated analog of trimethylsilylacetylene, where the terminal alkyne hydrogen is replaced by deuterium. This isotopic labeling is critical for applications requiring precise tracking of molecular pathways and enhanced spectroscopic analysis. It serves as a valuable deuterated building block in advanced organic synthesis and materials science research for the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Deuterium Labeling Agent: Used as a deuterium source in the synthesis of deuterated pharmaceuticals, agrochemicals, and organic materials for metabolic and stability studies.
• NMR Spectroscopy: Employed as an internal standard or a precursor for synthesizing deuterated NMR solvents and shift reagents.
• Mechanistic Studies: Essential in kinetic isotope effect (KIE) studies to elucidate reaction mechanisms in catalytic and organic transformations.
• Advanced Material Synthesis: A key monomer or precursor in the development of deuterated polymers, liquid crystals, and semiconductors for optoelectronic applications.
• Pharmaceutical Research: Utilized to create deuterated drug candidates, potentially improving pharmacokinetic profiles such as metabolic stability.
• Silicon Chemistry: Acts as a protected acetylene synthon in organosilicon and organometallic chemistry for constructing complex molecular architectures.

Basic Information

Item	Detail
Product Name	(Trimethylsilyl)Acetylene-D
CAS No.	7299-46-9
Molecular Formula	C5H9DSi
Molecular Weight	99.22 g/mol
Synonyms	Deutero(trimethylsilyl)acetylene; (Trimethylsilyl)acetylene-d; Ethynyltrimethylsilane-d; TMS-acetylene-D; Trimethylsilylacetylene-d1; (Deuteroethynyl)trimethylsilane; 1-Deutero-2-trimethylsilylacetylene
EINECS	Contact for details

Quality Control

Our (Trimethylsilyl)Acetylene-D is produced and handled under strict quality protocols. Each batch undergoes comprehensive analysis, including NMR (¹H, ¹³C, ²H) and GC-MS, to confirm isotopic purity, chemical identity, and the absence of protiated impurities. A Certificate of Analysis (COA) detailing deuterium content, chemical purity, and specific test results is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Deuterium Content (²H NMR)	≥ 98 atom % D
Purity (GC)	≥ 97%
Protiated Impurity (GC)	≤ 2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.