Description

Pyridine-D5 is a deuterated analog of pyridine, where all five hydrogen atoms are replaced with deuterium atoms. This isotopic labeling is critical for applications requiring high chemical stability and minimal spectral interference, such as NMR spectroscopy and mass spectrometry. It serves as an essential solvent and reagent in pharmaceutical research, agrochemical development, and advanced material science for studying reaction mechanisms and molecular structures.

Application

• NMR Spectroscopy: Used as a deuterated solvent for locking and shimming in proton NMR, providing a signal-free background.
• Mass Spectrometry: Employed as an internal standard or matrix in quantitative MS analysis due to its distinct mass shift.
• Pharmaceutical Research: Acts as a labeled intermediate in the synthesis of deuterated drug candidates for metabolic and pharmacokinetic (DMPK) studies.
• Chemical Reaction Studies: Utilized as a tracer to elucidate reaction pathways and mechanisms in catalytic and organic synthesis.
• Polymer Science: Serves as a probe solvent for investigating polymer-solvent interactions and diffusion processes.
• Agrochemical Development: Used in the synthesis of labeled pesticides and herbicides for environmental fate and metabolism studies.

Basic Information

Product Name	Pyridine-D5
CAS No.	7291-22-7
Molecular Formula	C5D5N
Molecular Weight	84.13 g/mol
Synonyms	Deuterated Pyridine; Perdeuteropyridine; Pyridine-d5; (2H5)Pyridine; Pentadeuteriopyridine; C5D5N; NSC 7391; EINECS 230-704-5
EINECS	230-704-5

Quality Control

Our Pyridine-D5 is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analysis to ensure high isotopic purity and chemical integrity. Certificates of Analysis (COA) detailing specifications for isotopic enrichment, chemical purity, and solvent residue are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container should be kept tightly sealed when not in use to prevent moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Isotopic Purity (D-Content)	≥ 99.5 atom % D
Assay (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%
Residue on Evaporation	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.