Description

(2S,3S,4E)-3,5-Bis(4-Hydroxyphenyl)-4-Pentene-1,2-Diol is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This compound matters as a sophisticated chiral building block, enabling the development of novel molecules with precise three-dimensional structures. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex natural products or active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents.
• Medicinal Chemistry Research: Used as a building block for constructing complex molecular scaffolds in drug discovery programs.
• Process Chemistry: Employed in the development and optimization of synthetic routes for target molecules at pilot and commercial scales.
• Natural Product Synthesis: Acts as a precursor in the total or semi-synthesis of structurally complex natural compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Asymmetric Synthesis Catalyst Development: May be used as a ligand precursor or a model substrate for developing new chiral catalysts.

Basic Information

Product Name	(2S,3S,4E)-3,5-Bis(4-Hydroxyphenyl)-4-Pentene-1,2-Diol
CAS No.	7288-11-1
Molecular Formula	C17H18O4
Molecular Weight	286.32 g/mol
Synonyms	3,5-Bis(4-hydroxyphenyl)-4-pentene-1,2-diol; (E)-3,5-Bis(4-hydroxyphenyl)pent-4-ene-1,2-diol; (2S,3S)-3,5-Bis(4-hydroxyphenyl)-4-pentene-1,2-diol; trans-3,5-Bis(4-hydroxyphenyl)-4-pentene-1,2-diol; (2S,3S,4E)-3,5-Bis(4-hydroxyphenyl)pent-4-ene-1,2-diol; 4-Pentene-1,2-diol, 3,5-bis(4-hydroxyphenyl)-, (2S,3S,4E)-; A potential synthetic intermediate for Combretastatin analogs.
EINECS	Contact for details

Quality Control

Our (2S,3S,4E)-3,5-Bis(4-Hydroxyphenyl)-4-Pentene-1,2-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.