Description

3-(2-Amino-Ethyl)-1H-Indole-5-Carboxylic Acid Ethyl Ester is a versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both an aminoethyl side chain and an ester group, makes it a valuable precursor for constructing complex heterocyclic systems and pharmacologically active molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of tryptamine derivatives, serotonin receptor modulators, and other central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of novel plant growth regulators and pesticides that leverage the indole scaffold.
• Biochemical Probe Synthesis: Serves as a starting material for creating fluorescent tags, enzyme inhibitors, and other molecular probes for life science research.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and specialty chemicals.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for producing custom compounds in contract manufacturing organizations (CMOs).

Basic Information

Product Name	3-(2-Amino-Ethyl)-1H-Indole-5-Carboxylic Acid Ethyl Ester
CAS No.	7272-54-0
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	5-Carbethoxy-3-(2-aminoethyl)indole; Ethyl 3-(2-Aminoethyl)-1H-indole-5-carboxylate; 5-(Ethoxycarbonyl)-3-(2-aminoethyl)indole; 3-(2-Aminoethyl)-1H-indole-5-carboxylic acid ethyl ester; 2-(5-Ethoxycarbonyl-1H-indol-3-yl)ethylamine; Tryptophan ethyl ester derivative; 7272-54-0; 5-Carbethoxy-3-(2-aminoethyl)indole
EINECS	Contact for details

Quality Control

Our 3-(2-Amino-Ethyl)-1H-Indole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.