Description

Aristolochic Acid Ⅲ is a naturally occurring nitrophenanthrene carboxylic acid derivative, recognized for its distinct chemical structure and biological activity. This high-purity reference standard is critical for ensuring analytical accuracy and research reproducibility in pharmaceutical and toxicological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and quality control laboratories engaged in the study of natural products, toxicology, and analytical method development.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the identification, assay, and impurity profiling of herbal medicines and related products.
• Toxicological Research: Used in studies investigating the nephrotoxic and carcinogenic mechanisms associated with aristolochic acids.
• Analytical Method Development: Essential for developing and validating precise HPLC, LC-MS, and other chromatographic methods for the detection of aristolochic acids.
• Biochemical Research: Employed as a tool compound in cell-based assays and molecular biology research to study specific biological pathways.
• Quality Control & Safety Testing: Critical for testing raw botanical materials and finished consumer products to ensure they are free from aristolochic acid contamination, supporting regulatory compliance.
• Academic Research: Used in universities and research institutes for chemical, pharmacological, and phytochemical studies.

Basic Information

Product Name	Aristolochic Acid Ⅲ
CAS No.	7267-92-7
Molecular Formula	C16H9NO6
Molecular Weight	311.25 g/mol
Synonyms	Aristolochic acid C; Aristolochic acid III; 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid; 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid; Aristolochic acid 3; Nitrophenanthrene carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our Aristolochic Acid Ⅲ is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We support compliance with relevant research and quality control standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the integrity of the material.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.