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Azidobis(Dimethylamino)Phosphine Oxide CAS NO 7219-78-5


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CAS No.:7219-78-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Azidobis(Dimethylamino)Phosphine Oxide is a specialized organophosphorus compound featuring an azide functional group. This unique structure makes it a valuable reagent in advanced chemical synthesis, particularly for the introduction of phosphorus-nitrogen functionalities. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures and as a precursor in materials science.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting phosphonate or phosphoramidate prodrugs.
  • Agrochemical Research: Serves as a key building block for developing new pesticides and herbicides with unique modes of action.
  • Ligand Synthesis: Employed in the preparation of specialized phosphine-azide ligands for catalysis and coordination chemistry.
  • Polymer Modification: Acts as a functional monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
  • Click Chemistry: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions due to its reactive azide group.
  • Materials Science: Investigated for the development of advanced materials, including flame retardants and specialty coatings.

Basic Information

Product Name Azidobis(Dimethylamino)Phosphine Oxide
CAS No. 7219-78-5
Molecular Formula C4H12N5OP
Molecular Weight 177.14 g/mol
Synonyms Azidobis(dimethylamino)phosphine oxide; (Dimethylamino)phosphine oxide azide; Phosphorazidic acid, bis(dimethylamide); Bis(dimethylamino)phosphinic azide; Azido-N,N,N',N'-tetramethylphosphonic diamide
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Quality Control

Our Azidobis(Dimethylamino)Phosphine Oxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, IR, and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its sensitivity, allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance White to off-white crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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