Description

Acetone-18O CAS NO 7217-26-7 is a stable isotope-labeled analog of acetone, where the standard oxygen atom is replaced with the Oxygen-18 (18O) isotope. This isotopic labeling is critical for applications requiring precise molecular tracking and analysis, offering a non-radioactive tracer for mechanistic studies. It is an essential reagent for researchers and quality control laboratories in the pharmaceutical, environmental science, and advanced materials sectors who require high-purity isotopic compounds for mass spectrometry, NMR spectroscopy, and metabolic pathway research.

Application

• Isotopic Tracer in Metabolic Studies: Used in pharmaceutical and biochemical research to trace metabolic pathways and drug metabolism using techniques like GC-MS and LC-MS.
• Internal Standard for Mass Spectrometry: Serves as a high-purity quantitative standard for the accurate measurement of acetone and related compounds in analytical chemistry.
• NMR Spectroscopy Solvent: Employed as a deuterated solvent alternative or a specific probe in nuclear magnetic resonance (NMR) for structural elucidation.
• Chemical Synthesis Intermediate: Utilized in the synthesis of more complex 18O-labeled compounds for research and diagnostic purposes.
• Environmental Fate Studies: Applied in research to track the environmental degradation and transformation pathways of volatile organic compounds.
• Quality Control & Reference Material: Acts as a certified reference material (CRM) for calibrating instruments and validating analytical methods in regulated laboratories.

Basic Information

Product Name	Acetone-18O
CAS No.	7217-26-7
Molecular Formula	C3H618O
Molecular Weight	60.07 g/mol (for 18O labeled)
Synonyms	Acetone-18O; [18O]Acetone; 2-Propanone-18O; (18O)Acetone; Isotopic Acetone; Oxygen-18 Labeled Acetone; Dimethyl ketone-18O; CAS 7217-26-7
EINECS	Contact for details

Quality Control

Every batch of Acetone-18O is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity, which is paramount for research integrity. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residue profiles. Our quality commitment aligns with the needs of GMP/GLP-compliant laboratories, and specifications can be tailored to meet specific research or compendial standards (e.g., USP, Ph. Eur.) upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at room temperature (15-25°C/59-77°F). Keep away from heat, sparks, open flames, and strong oxidizing agents. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Enrichment (18O)	≥ 95 atom % (Typical 97-99%)
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.