Description

5-Hydroxy-2-Thiophenecarboxylic Acid Ethyl Ester is a versatile heterocyclic building block and ester derivative of thiophene. This compound is valued for its unique molecular structure, which combines a hydroxyl group and an ester functionality on a thiophene ring, making it a key intermediate in advanced organic synthesis. It is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of conductive polymers, organic semiconductors, and advanced polymeric materials.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, including Suzuki coupling and other cross-coupling reactions, to construct more complex heterocyclic systems.
• Ligand and Catalyst Development: Utilized for creating novel ligands in coordination chemistry and catalysis due to its potential donor sites.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and organic pigments with specific light-absorption properties.

Basic Information

Product Name	5-Hydroxy-2-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	7210-60-8
Molecular Formula	C7H8O3S
Molecular Weight	172.20 g/mol
Synonyms	Ethyl 5-Hydroxythiophene-2-carboxylate; 5-Hydroxythiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic Acid, 5-Hydroxy-, Ethyl Ester; Ethyl 5-Hydroxy-2-thiophenecarboxylate; 5-Hydroxy-2-thiophenecarboxylic acid ethyl ester; 5-Hydroxythiophene-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-5-hydroxythiophene
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-Thiophenecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.