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(2R)-2-[3-[[(2R)-2-Hydroxy-3,3-Dimethyl-4-Phosphonooxybutanoyl]Amino]Propanoylamino]-3-Sulfanylpropanoic Acid CAS NO 7196-09-0
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CAS No.:7196-09-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(2R)-2-[3-[[(2R)-2-Hydroxy-3,3-Dimethyl-4-Phosphonooxybutanoyl]Amino]Propanoylamino]-3-Sulfanylpropanoic Acid is a sophisticated, high-purity chiral compound featuring a unique molecular scaffold that combines a phosphonooxy group with a sulfanyl (thiol) moiety. This structure is critical for its role as a key intermediate or building block in advanced pharmaceutical synthesis and biochemical research. It is primarily sought after by R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors. The compound's specific stereochemistry and functional groups make it essential for developing targeted therapeutics and conducting mechanistic studies.
Application
- Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates, particularly those targeting enzymatic pathways.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate mechanisms involving phosphorylation and thiol chemistry.
- Peptide & Prodrug Synthesis: Its functional groups make it valuable for constructing complex peptide analogs or designing prodrugs with specific release profiles.
- Ligand Development: Employed in the development of specialized ligands for catalysis or metal chelation in medicinal chemistry.
- Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
Basic Information
| Product Name | (2R)-2-[3-[[(2R)-2-Hydroxy-3,3-Dimethyl-4-Phosphonooxybutanoyl]Amino]Propanoylamino]-3-Sulfanylpropanoic Acid |
| CAS No. | 7196-09-0 |
| Molecular Formula | C12H23N2O9PS |
| Molecular Weight | 402.36 g/mol |
| Synonyms | L-Cysteine, N-[3-[[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)-1-oxobutyl]amino]-1-oxopropyl]-; (R)-2-((R)-3-((2-Hydroxy-3,3-dimethyl-4-phosphonooxybutanoyl)amino)propanamido)-3-mercaptopropanoic acid; Fosfomycin cysteine adduct derivative; Thiol-containing phosphonate derivative; Chiral cysteine-phosphonate conjugate; Contact for additional synonyms. |
| EINECS | Contact for details |
Quality Control
Our (2R)-2-[3-[[(2R)-2-Hydroxy-3,3-Dimethyl-4-Phosphonooxybutanoyl]Amino]Propanoylamino]-3-Sulfanylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and related substances are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and minimize degradation. Due to its hygroscopic nature, the container must be kept in a dry environment. For long-term storage, desiccants are recommended.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Single Unknown Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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