Description

Acetonitrile, [2-14C] CAS NO 7183-57-5 is a carbon-14 labeled isotopologue of acetonitrile, a fundamental polar aprotic solvent and versatile chemical intermediate. This radiolabeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to trace molecular pathways with high specificity. It is a critical reagent for pharmaceutical R&D, agrochemical development, and environmental science laboratories engaged in advanced analytical and tracer applications.

Application

• Pharmaceutical Research: As a radiolabeled precursor or solvent in the synthesis of carbon-14 labeled drug candidates for metabolism and absorption, distribution, metabolism, and excretion (ADME) studies.
• Metabolic Pathway Tracing: Used to investigate biochemical pathways in plants, animals, and microorganisms, providing insights into biotransformation processes.
• Analytical Chemistry: Serves as a component in mobile phases for High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) when radiolabel detection is required.
• Environmental Fate Studies: Employed in research to track the degradation, movement, and persistence of chemical compounds or pollutants in environmental systems.
• Agrochemical Development: Utilized in the synthesis of labeled pesticides or herbicides to study their environmental impact and metabolic fate in target organisms.
• Chemical Synthesis: Acts as a labeled building block or solvent in organic synthesis for creating complex molecules with a radioactive tracer for mechanistic studies.

Basic Information

Product Name	Acetonitrile, [2-14C]
CAS No.	7183-57-5
Molecular Formula	C14CH3N or C12C14H3N
Molecular Weight	~42.04 g/mol (varies with specific activity)
Synonyms	Acetonitrile-2-14C; Methyl cyanide-2-14C; Cyanomethane-2-14C; Ethanenitrile-2-14C; [2-14C]Acetonitrile; Acetonitrile (carbon-14 labeled); RadiolaBeled Acetonitrile; ACN-14C
EINECS	Contact for details

Quality Control

Every batch of Acetonitrile, [2-14C] is produced and analyzed under stringent quality systems to ensure radiochemical purity, chemical purity, and specific activity meet the exacting standards required for research. Certificates of Analysis (COA) are provided, detailing key parameters such as radionuclidic purity, radiochemical concentration, and identification. Our commitment to cGMP and ISO 9001 principles ensures traceability and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a dedicated, well-ventilated area for radioactive materials at recommended temperatures (typically 2-8°C or as specified on the label). Due to its highly volatile nature, ensure containers are securely sealed and stored upright to prevent leakage. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (GC)	≥ 99%
Specific Activity	Customer specified (mCi/mmol)
Radionuclidic Purity	≥ 99% 14C
Concentration	As per customer requirement

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.