Description

Metazocine Hydrobromide is a synthetic benzomorphan derivative, recognized for its potent pharmacological activity as a κ-opioid receptor agonist. This high-purity compound is critical for advancing research in neuropharmacology and analgesic development, offering a valuable tool for studying receptor mechanisms and pain pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and analytical reference standard providers for preclinical studies and method development.

Application

• Pharmacological Research: A key reference standard and active agent in studies investigating κ-opioid receptor function, signal transduction, and ligand-receptor interactions.
• Analgesic Development: Serves as a lead compound or comparative agent in the research and development of novel non-addictive or reduced-addiction potential pain medications.
• Neurochemical Studies: Used in vitro and in vivo models to explore the role of opioid systems in pain perception, addiction, and other neurological processes.
• Analytical Standard: Provides a certified reference material for quality control and method validation in HPLC, LC-MS, and other analytical techniques within pharmaceutical testing laboratories.
• Biochemical Assays: Employed in high-throughput screening (HTS) and binding assays to evaluate the potency and selectivity of new chemical entities targeting opioid receptors.

Basic Information

Product Name	Metazocine Hydrobromide
CAS No.	7148-43-8
Molecular Formula	C₁₅H₂₁NO·HBr
Molecular Weight	312.25 g/mol
Synonyms	Metazocine HBr; 1,2,3,4,5,6-Hexahydro-8-hydroxy-3,6,11-trimethyl-2,6-methano-3-benzazocin-10-ol Hydrobromide; Win 13,098; NIH 7956; 2'-Hydroxy-2,5,9-trimethyl-6,7-benzomorphan Hydrobromide; (±)-Metazocine Hydrobromide
EINECS	Contact for details

Quality Control

Our Metazocine Hydrobromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced chromatographic and spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.