Description

5-Acetamidoindole is a versatile and high-purity organic building block, specifically an N-acetylated indole derivative, with the CAS registry number 7145-71-3. This compound is a critical intermediate in the synthesis of complex molecules, valued for its role in constructing indole-based pharmacophores and advanced materials. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality raw materials for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Biochemical Research: Serves as a building block for probes, inhibitors, and labeled compounds used in enzymatic and receptor binding studies.
• Material Science: Employed in the creation of organic electronic materials, dyes, and photostabilizers due to its conjugated indole structure.
• Academic & Contract Research: A fundamental reagent for method development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	5-Acetamidoindole
CAS No.	7145-71-3
Molecular Formula	C10H10N2O
Molecular Weight	174.20 g/mol
Synonyms	1H-Indole-5-acetamide; N-(1H-Indol-5-yl)acetamide; 5-Acetamido-1H-indole; 5-Acetylaminoindole; 5-(Acetylamino)indole; Acetamide, N-(5-indolyl)-; 5-Indolylacetamide
EINECS	Contact for details

Quality Control

Our 5-Acetamidoindole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	198°C - 202°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.