Description

α-(4-Bromophenyl)-1H-Benzimidazole-2-Methanol is a high-purity, functionalized benzimidazole derivative characterized by its brominated phenyl and hydroxymethyl substituents. This compound is a crucial advanced intermediate for the synthesis of complex molecules, offering a versatile scaffold for pharmaceutical and agrochemical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting various enzyme families where the benzimidazole core is pharmacologically active.
• Agrochemical Research: Used in the development of novel fungicides, herbicides, or plant growth regulators, leveraging its halogenated aromatic system for bioactivity.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Precursor: Employed in the research of organic electronic materials, such as OLEDs or conductive polymers, due to its conjugated benzimidazole structure.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	α-(4-Bromophenyl)-1H-Benzimidazole-2-Methanol
CAS No.	7104-86-1
Molecular Formula	C14H11BrN2O
Molecular Weight	303.16 g/mol
Synonyms	2-[(4-Bromophenyl)hydroxymethyl]-1H-benzimidazole; (4-Bromophenyl)(1H-benzimidazol-2-yl)methanol; α-(4-Bromophenyl)-1H-benzimidazole-2-methanol; 1H-Benzimidazole-2-methanol, α-(4-bromophenyl)-; (4-Bromobenzyl)benzimidazol-2-yl methanol
EINECS	Contact for details

Quality Control

Our α-(4-Bromophenyl)-1H-Benzimidazole-2-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for advanced synthetic intermediates. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.